Learn about Tofranil (Imipramine) may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and related medications. Generic imipramine is available in tablet form in the same doses as those found in Tofranil and Tofranil PM. The brand name Tofranil comes in 10 milligram (mg), 25 mg, and 50 mg tablets, while the. Tofranil is available in tablet form in 10 mg, 25 mg, and 50 mg strengths. There is also an injection available. There is also an injection available. Tofranil-PM tablets are available in 75 mg. Imipramine oral tablet is available as a generic drug and as the brand-name drug Tofranil. Learn about side effects, warnings, dosage, and more. Learn about side effects, warnings, dosage, and. Find patient medical information for Tofranil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Tofranil™ is supplied in tablet form for oral administration. Tofranil, imipramine hydrochloride USP, the original tricyclic antidepressant, is a member of the dibenzazepine group of compounds. Imipramine (Tofranil, Tofranil-PM) is an antidepressant medication prescribed for the treatment of depression, bedwetting, and chronic pain. Side effects, drug interactions, pregnancy safety, and precautions should be reviewed prior to taking this medication. All people who take Tofranil (imipramine tablets) need to be watched closely. Call the doctor right away if signs like low mood (depression), nervousness, restlessness, grouchiness, panic attacks, or changes in mood or actions are new or worse. Call the doctor right away if any thoughts or actions of suicide occur. Imipramine, sold under the brand name Tofranil among others, is a tricyclic antidepressant (TCA) which is used mainly in the treatment of depression. It can also reduce symptoms of agitation and anxiety. This site uses cookies. By continuing to browse the site you are agreeing to our policy on the use of cookies. By continuing to browse the site you are agreeing to our policy on the use of cookies. Continue.